Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011824
Fusion event
HBV-PAPPA2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1778
Orient
+
Integrated sequence
GCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAG| |GAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAG
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
End
176547681/176578545 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/610066; hsa-mir-1182/Downstream/450818;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/370870, chr1-CpG: 44/Downstream/585711
Upstream sequence
TCTGAGTCAAGACTCTCATGACTCCATTTGACTTCAGGAGCAGAGTGGGAACAAGGAAATACAACCCATCCTTTCTTGTTCCTGTGGTAAATTCATAGAT
Downstream sequence
GTCTAAGATAGGCTCTTGTCATCAAGGGACTCTCAGATTTCTTCACAAATAGCAGCAGTTCAACAAGGCTCAGCAACCTGCAACAAGATCacttttacta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.