Fusion event
HBV-CTNNA3 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|precore/core protein|
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
End
68266790/66507032 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1265/Upstream/3133984; hsa-mir-107/Downstream/896319;
Nearest cancer related gene
Upstream sequence
ATATTGGTCATCTTTTATCCCAACTCCTATTAAATAAATATCATATTGAGATTTAATAGTGCTTAGTTTTGATGCAGTTAATTTTAACATTTTGCTCTTG
Downstream sequence
CTAACATTATTATGTGTTTTTTGGCATCAGCTTATGAAAGAACATGGAAAATCAATTTATTTTCCATTTTCTTTGTCAAATTTAGATTAAAACTTTGTAG
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.