hsa-mir-6826-3p _LIHC.png
hsa-mir-4470 _LIHC.png
CTNNA3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011839
Fusion event
HBV-CTNNA3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1815
Orient
-
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr10
Cytoband
q21.3
Reference genome
End
68266790/66507032 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1265/Upstream/3133984; hsa-mir-107/Downstream/896319;
Nearest cancer related gene
CTNNA3(TSG, No orient, 0)
Upstream sequence
ATATTGGTCATCTTTTATCCCAACTCCTATTAAATAAATATCATATTGAGATTTAATAGTGCTTAGTTTTGATGCAGTTAATTTTAACATTTTGCTCTTG
Downstream sequence
CTAACATTATTATGTGTTTTTTGGCATCAGCTTATGAAAGAACATGGAAAATCAATTTATTTTCCATTTTCTTTGTCAAATTTAGATTAAAACTTTGTAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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