Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011844
Fusion event
HBV-LOC441601 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2138
Orient
+
Integrated sequence
AGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCC| |AGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGA
Host Sequence
Chromosome
chr11
Cytoband
p11.12
Reference genome
Start
End
50249162/50289991 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-129-2/Upstream/2193133; hsa-let-7a-2/Downstream/6453882;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/10940, chr11-CpG: 59/Downstream/8093
Upstream sequence
caactaattttttttattttttgtagagacaggatgtcactatgttgcctagtctgaggcctcaagcaatcctcctgccttggtccccaaagtgctggga
Downstream sequence
ttacaggcgtaagccactgcatctggccTGAACCTATCCATCTTTGAAAAAAAAATTAAGTTTTGCTTCTTTTTATTAATCATTATATAAAACACTAAAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.