VISDB Viral Integration Site DataBase

VIS ID

TVIS10011852

Fusion event

HBV-RILPL1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1894

Orient

+

Integrated sequence

ATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGC| |TTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCT

Chromosome

chr12

Cytoband

q24.31

Reference genome

Start

End

123978669/123494122 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-7703 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-548ao-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-342-3p ; hsa-mir-5693 ; hsa-mir-383-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-1228-3p ; hsa-mir-449b-3p ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-6869-5p ; hsa-mir-4279 ; hsa-mir-1200 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-377-5p ; hsa-mir-1227-3p ; hsa-mir-1247-3p ; hsa-mir-1262 ; hsa-mir-2467-3p ; hsa-mir-3145-5p ; hsa-mir-339-5p ; hsa-mir-3667-5p ; hsa-mir-3940-3p ; hsa-mir-4252 ; hsa-mir-4257 ; hsa-mir-4421 ; hsa-mir-4701-3p ; hsa-mir-4725-5p ; hsa-mir-4797-5p ; hsa-mir-490-3p ; hsa-mir-542-3p ; hsa-mir-550b-2-5p ; hsa-mir-5699-3p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6828-5p ; hsa-mir-7851-3p

Nearest miRNA

hsa-let-7i/Upstream/129279; hsa-mir-3612/Downstream/42287;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/35668, chr12-CpG: 137/Downstream/38924

Upstream sequence

gatccacccgccttggcctccccaagtgctgggattacaggtgtgggccactgcgcctggccCTGTCCCTGCCTCTTGACTTCACCAAGCCCTCCCCTGA

Downstream sequence

TCTTATACTCCTCTCTCCCAGCTGCGCGAAacagtgaacctactgagtcaagctcattcccctcacttgtcagatgacgaaattgaccaccaaagagatg