VISDB Viral Integration Site DataBase

VIS ID

TVIS10011853

Fusion event

HBV-TMEM132B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2802

Orient

+

Integrated sequence

ATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAG| |CGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCA

Chromosome

chr12

Cytoband

q24.32

Reference genome

Start

End

125936423/125451877 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-221-3p ; hsa-mir-181a-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-567 ; hsa-mir-602 ; hsa-mir-8485 ; hsa-mir-377-3p ; hsa-mir-744-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-378a-5p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-6131 ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-505-3p ; hsa-mir-4735-5p ; hsa-mir-4762-5p ; hsa-mir-1208 ; hsa-mir-1273f ; hsa-mir-1291 ; hsa-mir-1304-3p ; hsa-mir-328-3p ; hsa-mir-4290 ; hsa-mir-4469 ; hsa-mir-6760-3p ; hsa-mir-6775-3p ; hsa-mir-6851-3p

Nearest miRNA

hsa-let-7i/Upstream/536218; hsa-mir-3612/Downstream/2842215;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/120606, chr12-CpG: 24/Downstream/81677

Upstream sequence

agagagaatttatgaatagcatgaatagttagtttacttttgcatgtgcccagaggcactagcattccaggatatcaggaaaaaactcagatcactttaa

Downstream sequence

ttcatgttcagggactgactgtccatgtctgattcactcttattcccatggtgtggttctttggggttcccaaacaaattaaagtgtgttgggggaagga