VISDB Viral Integration Site DataBase

VIS ID

TVIS10011854

Fusion event

HBV-TMEM132B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1731

Orient

-

Integrated sequence

ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA| |CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACC

Chromosome

chr12

Cytoband

q24.32

Reference genome

Start

End

125936672/125452126 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-221-3p ; hsa-mir-181a-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-567 ; hsa-mir-602 ; hsa-mir-8485 ; hsa-mir-377-3p ; hsa-mir-744-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-378a-5p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-6131 ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-505-3p ; hsa-mir-4735-5p ; hsa-mir-4762-5p ; hsa-mir-1208 ; hsa-mir-1273f ; hsa-mir-1291 ; hsa-mir-1304-3p ; hsa-mir-328-3p ; hsa-mir-4290 ; hsa-mir-4469 ; hsa-mir-6760-3p ; hsa-mir-6775-3p ; hsa-mir-6851-3p

Nearest miRNA

hsa-let-7i/Upstream/536467; hsa-mir-3612/Downstream/2841966;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/120855, chr12-CpG: 24/Downstream/81428

Upstream sequence

gtgtctgttttaggtttgtgaggttgtcgaaagttcttagcctcttagctgacccccgtctggtattagcaaatgcccacagaagaaaagaggcccccag

Downstream sequence

ttctgggctcatcttcatgcacctatctcatcccctggattccagctgtgtaattttttacctttaaaattttttttgatgtctgctgtaagtcatattt