VISDB Viral Integration Site DataBase

VIS ID

TVIS10011862

Fusion event

HBV-HS6ST3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2837

Orient

+

Integrated sequence

ACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAAC| |AAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATC

Chromosome

chr13

Cytoband

q32.1

Reference genome

Start

End

96861445/96209191 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-5589-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-574-5p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-592 ; hsa-mir-513a-5p ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-597-5p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-4445-5p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-6767-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485

Nearest miRNA

hsa-mir-1297/Upstream/3718971; hsa-mir-1267/Downstream/218038;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/117283, chr13-CpG: 35/Downstream/784949

Upstream sequence

ATAAGTTTTGAATGCGGATTTGACTAGTAGGAGATACAGAGTGtagacatcaatatagtaatatagatggaaagatggattgtctatgtaattccttgat

Downstream sequence

cttacaagggagagaattgagaaaatgagccattgagcaacttacagaagttgtgggttagcggtagcggggatcatattagaacaaggtgtctcaactc