VISDB Viral Integration Site DataBase

VIS ID

TVIS10011868

Fusion event

HBV-BCAS3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1645

Orient

-

Integrated sequence

ACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCC| |AAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGG

Chromosome

chr17

Cytoband

q23.2

Reference genome

Start

End

59067184/60989823 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1278 ; hsa-mir-1285-3p ; hsa-mir-2861 ; hsa-mir-3187-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-3664-5p ; hsa-mir-3667-3p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-4714-5p ; hsa-mir-514a-5p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-6734-3p ; hsa-mir-6860 ; hsa-mir-6883-3p

Nearest miRNA

hsa-mir-10226/Upstream/946718; hsa-mir-1250/Downstream/1954392;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/311704, chr17-CpG: 720/Downstream/405876

Upstream sequence

TCTTTGCATTTCACCTCTCTTCAGGATCCTGTATCCCTGACTATTGAAGTAACATTCTACCTAATGGAGTTTTGATCAACAGTCATTGTGAAATGCATCT

Downstream sequence

GTAGAGTAAATTTTTATTTATTACCTGATCTTAGGTACATTTGGTAATGAGGCAATCATTTATATTCATATTTGGTGATGTGTGATACTCTTAGAAAAAT