VISDB Viral Integration Site DataBase

VIS ID

TVIS10011871

Fusion event

HBV-CHD3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1821

Orient

+

Integrated sequence

TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

7796392/7893074 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-1296-5p ; hsa-mir-1226-3p ; hsa-mir-16-5p ; hsa-mir-204-3p ; hsa-mir-3153 ; hsa-mir-3611 ; hsa-mir-4455 ; hsa-mir-4463 ; hsa-mir-451b ; hsa-mir-4646-5p ; hsa-mir-4668-5p ; hsa-mir-4688 ; hsa-mir-486-3p ; hsa-mir-5681a ; hsa-mir-609 ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-6743-5p ; hsa-mir-6772-5p ; hsa-mir-873-3p

Nearest miRNA

hsa-mir-1253/Upstream/669695; hsa-mir-10226/Downstream/194982;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/7301, chr17-CpG: 27/Downstream/16104

Upstream sequence

tctcactttgttgcccaggcttatctcatagccctgggctcaagcaatcctcctgcttcagcctggaattacaggcatgagccaccgtgcctggccTGTA

Downstream sequence

TTTCTTTTTTAATGCTTTTTTAAACCTGTTCTTTCCCCGCTTTTTTTAAACTTCtttttatttatttttttaaatGGCTGTTTTTCCTAATAGGACATAT