Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011880
Fusion event
HBV-CDH19 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1823
Orient
-
Integrated sequence
TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
Start
End
64184902/66517665 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1-2/Upstream/8066507; hsa-mir-5011/Downstream/563919;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/766261, chr18-CpG: 83/Downstream/998335
Upstream sequence
ACATAGGTATTTGAGTAAATGTTTGGATTCCTCCAGAGTAGAGTGTGACTACTCTGGCATTTTTATTTTCTATGATCAATTTATTATCCATCCAAAGTAG
Downstream sequence
ATAGATATAAGACATCCTTTTACCTGCCATTTTCTCTGGCTGTTTGAGCATGTGGGAAATGAGAAAAGAATCATCTTCataaattaaaaatatgtataaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.