hsa-mir-4700-5p _LIHC.png
PIN1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011886
Fusion event
HBV-PIN1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1622
Orient
-
Integrated sequence
GGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCG| |TGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTT
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
End
9952889/9842213 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1227/Upstream/1452833; hsa-let-7e/Downstream/196141;
Nearest cancer related gene
PIN1(TSG, No orient, 0)
Upstream sequence
ACCTGGTGGAAGCTGTGGGAGGAATTGGAGCAAGAGGCGGTGTGACTTGAACTTGGGGGCTGGAAGTGGAAGAAGAAGTGAGAGGGAGCAGACCCGAGAG
Downstream sequence
AGATTCAGGAGGCAGGATAGAGAGGACTGGGTGATGGATTAGGTGGGCAAGGGTGGGATGTCTGGGGGAGGGTCAGGGCAGAACAGCGTGGCCCACcctg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate