VISDB Viral Integration Site DataBase

VIS ID

TVIS10011887

Fusion event

HBV-GULP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1816

Orient

-

Integrated sequence

CTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCA| |TGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC

Chromosome

chr2

Cytoband

q32.1

Reference genome

Start

End

189184616/188319889 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-7975 ; hsa-mir-3606-5p ; hsa-mir-5571-3p ; hsa-mir-627-3p ; hsa-mir-448 ; hsa-mir-153-3p ; hsa-mir-190a-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p

Nearest miRNA

hsa-mir-10b/Upstream/22301; hsa-mir-1244-1/Downstream/658203;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/26897, chr2-CpG: 26/Downstream/1121542

Upstream sequence

TTTTATTTTGTTGATTCAGAGCTCTTTTTTTGTCCTATTCTTTCTTTCATTTGATCTTTTTTGCCCTTTTTACTTTCTTCTATCATTGAGCTTAATATCT

Downstream sequence

TGGAGTATGTTTGATGGTGATAAGTTTAGTATGgggtttcccagtcttggcaatattgacattttgggaaagacaactctttgttgtcaagggagtggcc