VISDB Viral Integration Site DataBase

VIS ID

TVIS10011909

Fusion event

HBV-PLOD2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2489

Orient

+

Integrated sequence

CTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTG| |GGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACA

Chromosome

chr3

Cytoband

q24

Reference genome

Start

End

145873940/146156153 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-221-3p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-425-5p ; hsa-mir-615-3p ; hsa-mir-183-5p ; hsa-mir-1260b ; hsa-mir-136-5p ; hsa-mir-26a-5p

Nearest miRNA

hsa-let-7g/Upstream/11718247; hsa-mir-1224/Downstream/5409723;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/2182716, chr3-CpG: 97/Downstream/4490

Upstream sequence

gtgggcgggttacttgagcccagagttcgagaccagactgggcaacatagggtgaaccctgtctctataaaaaataaaaaacttaggtggcacatgcctg

Downstream sequence

CACCACAGGAATCACCGGCAAATTCTAAAATGAAAAACAGGTCTCTGAAATGCCCAGAGCCAGCTGCTACTGTCCAGAAGCCAGCTCCTTCCCACAGAGC