VISDB Viral Integration Site DataBase

VIS ID

TVIS10011918

Fusion event

HBV-FOXP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2371

Orient

+

Integrated sequence

GTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTA| |GAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATA

Chromosome

chr3

Cytoband

p13

Reference genome

Start

End

71149204/71100053 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-122-5p ; hsa-mir-34a-5p ; hsa-mir-335-5p ; hsa-mir-33a-5p ; hsa-mir-22-3p ; hsa-mir-1229-3p ; hsa-mir-320a ; hsa-mir-100-5p ; hsa-mir-9-5p ; hsa-mir-512-5p ; hsa-mir-218-5p ; hsa-mir-4276 ; hsa-mir-105-5p ; hsa-mir-7853-5p ; hsa-mir-578 ; hsa-mir-548aw ; hsa-mir-526b-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1181 ; hsa-mir-5195-5p ; hsa-mir-4480 ; hsa-mir-577 ; hsa-mir-497-3p ; hsa-mir-1277-5p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-let-7c-3p ; hsa-mir-486-5p ; hsa-mir-8485 ; hsa-mir-649 ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6882-3p ; hsa-mir-27b-5p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-556-5p ; hsa-mir-512-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-367-5p ; hsa-mir-4639-5p ; hsa-mir-4517 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-6507-3p ; hsa-mir-1264 ; hsa-mir-431-5p ; hsa-mir-561-3p ; hsa-mir-6821-5p

Nearest miRNA

hsa-let-7g/Upstream/2051018; hsa-mir-12124/Downstream/441917;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/34383, chr3-CpG: 155/Downstream/481369

Nearest cancer related gene

FOXP1(TSG, No orient, 0)

Upstream sequence

caagatatagaactattctatcactaaaaagatcttggtcgggcgcagtggctcatgcctataatcccagcactttggaaggctgaggcaggtggatctt

Downstream sequence

GACATGGATCAGCATAGACTATGGTCAGATAGGTCTATGGCAAGCTtggcaaacagaaggtgcacatagcacttctcccatctccagtgcccatggcaga