AASDH _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011924
Fusion event
HBV-AASDH integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2474
Orient
+
Integrated sequence
GAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGG| |TGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTAT
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
57238604/56372438 (Hg38)
End
57238604/56372438 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4B
Target gene
AASDH
miRNAs that regulate target gene
hsa-mir-10b-5p ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-95-5p ; hsa-mir-605-5p
Nearest miRNA
hsa-mir-12113/Upstream/3659691; hsa-mir-1243/Downstream/4550181;
Nearest TSS
ENST00000502981/Upstream/55775; ENST00000602927/Downstream/11861;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/56457, chr4-CpG: 33/Downstream/14864
Upstream sequence
caggagttcaagaccagttcaagacctggccaaaatggttaaaccctgtctctactaaaaatacaaaaattagctaggcgtggtgatgggcacctgtaat
Downstream sequence
CCTTTCTATTTAGCATTTTCTTTCAGTATCTGAACAAAAAGCAGAATAAGAATATATGTGGTTAGGCTCTTATACAGCATGGATAGTCATTGTGGAGCCT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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