VISDB Viral Integration Site DataBase

VIS ID

TVIS10011929

Fusion event

HBV-CAMK4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2091

Orient

+

Integrated sequence

TCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGG| |GAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGT

Chromosome

chr5

Cytoband

q22.1

Reference genome

Start

End

110793898/111458200 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-185-5p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6509-3p ; hsa-mir-196a-3p ; hsa-mir-3128 ; hsa-mir-4746-5p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-6807-5p ; hsa-mir-922 ; hsa-mir-1245b-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6867-5p ; hsa-mir-622 ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-3156-3p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-3605-5p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4301 ; hsa-mir-329-5p ; hsa-mir-5197-3p

Nearest miRNA

hsa-mir-10397/Upstream/944285; hsa-mir-103a-1/Downstream/4797543;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/233452, chr5-CpG: 51/Downstream/53922

Upstream sequence

atgtcaaatgcttttttgattttttccatggtaaccttgcattactaacagaaattcacttggtcatgtgcctaatcttatatatgttgctggattttac

Downstream sequence

CAGTTGAGTAGTGCCAGGTAAAGGAAAAGTAGGGACAGATACAGGGTGGCGAGGAAGGGTCATCCAGAGCTCATCTTGTTCTTGATCATGGAGAGGAAAG