Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011931
Fusion event
HBV-LCP2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1821
Orient
-
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
End
169719359/170292355 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/263789; hsa-mir-10523/Downstream/1094301;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/59130, chr5-CpG: 64/Downstream/211510
Upstream sequence
agaaatctatctgactcattaatgaaggatcttgcaatatgataaaacatgttcgaaaaaaaattagaacaacagtttatatggtccaataggaaagtta
Downstream sequence
ggtggtggtgagctcaccatcactgaaggaattcaagaagatgttggtagcagagatgtaatataagaaatggattggtgttctctgggggcaagctgga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.