VISDB Viral Integration Site DataBase

VIS ID

TVIS10011941

Fusion event

HBV-FOXP2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1871

Orient

+

Integrated sequence

GTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGC| |CTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTC

Chromosome

chr7

Cytoband

q31.1

Reference genome

Start

End

114171344/114531289 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-95-5p ; hsa-mir-3613-3p ; hsa-mir-548p ; hsa-mir-4422 ; hsa-mir-6835-3p ; hsa-mir-190a-5p ; hsa-mir-1273h-3p ; hsa-mir-129-5p ; hsa-mir-2467-3p ; hsa-mir-3678-3p ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-6516-5p

Nearest miRNA

hsa-mir-10525/Upstream/12059758; hsa-mir-10399/Downstream/122056;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/443549, chr7-CpG: 61/Downstream/390826

Upstream sequence

TGATGGACTGAGGCAGTAAATTAAATGCAGCGGTGAAAACACGACCAACCTACAGTTGAACTCAAAGTGAGAAAAGAATGATTCAGAAACTCCCCCTAAT

Downstream sequence

ATAGAAGTGGCAAGTGATTTTTAAATTAATATTTGTGTCATTTGACACCTAACATTTTATATTGATGGAAGTGTTTTATCTAATAATCTTTCATTTTTTG