VISDB Viral Integration Site DataBase

VIS ID

TVIS10011942

Fusion event

HBV-AHCYL2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2071

Orient

+

Integrated sequence

TTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGC| |AAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAA

Chromosome

chr7

Cytoband

q32.1

Reference genome

Start

End

128907907/129268066 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-185-5p ; hsa-mir-92a-3p ; hsa-mir-4531 ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4650-3p ; hsa-mir-3132 ; hsa-mir-197-5p ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3185 ; hsa-mir-4768-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6755-5p ; hsa-mir-3123 ; hsa-mir-5197-3p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-3202 ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-4532 ; hsa-mir-6895-5p ; hsa-mir-1273e ; hsa-mir-6807-5p ; hsa-mir-3672 ; hsa-mir-6864-3p ; hsa-mir-6894-5p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-4649-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-1277-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-3976 ; hsa-mir-6868-3p ; hsa-mir-3124-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-670-3p ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-1285-3p ; hsa-mir-196a-3p ; hsa-mir-3187-5p ; hsa-mir-3606-5p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-661 ; hsa-mir-6732-3p ; hsa-mir-6849-3p ; hsa-mir-6860 ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-10525/Upstream/1060123; hsa-mir-10399/Downstream/502317;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/42252, chr7-CpG: 94/Downstream/165815

Upstream sequence

aaaacacaacacctctatgcaatattattgtccacacaaaatgttggtaggggggaacctgaatgaaatcaagcatctagatttaactaccagcttgcat

Downstream sequence

TTTACTCCTAGTTCTACTAGGAGTAAACGTAGTAGTTTAAACTAGTAATTAGTAATTTAGTAAATTTAAACTAATAATTTCCAAGTCAGAATTTTAACAG