VISDB Viral Integration Site DataBase

VIS ID

TVIS10011948

Fusion event

HBV-AUTS2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1887

Orient

-

Integrated sequence

GGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTT| |GGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAG

Chromosome

chr7

Cytoband

q11.22

Reference genome

Start

End

70110090/70645104 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-222-3p ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-1183/Upstream/3530707; hsa-mir-10399/Downstream/662568;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/48634, chr7-CpG: 218/Downstream/48670

Upstream sequence

cctcagcctcctgaatggctggaagtacaggtgcccaccaccatgcctggctaatttttgtacttttagtagagatggggtttcactatgttgtccaggc

Downstream sequence

CATCTTCCTTCAGGCTCACAAGCGTTCTTCACCCAAAGGGAGGGAGATTAATTGACTTCTTTTATCTTCCATTCAAATGAGGCTTTCATGTGAATCGCTC