Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011951
Fusion event
HBV-NXPH1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1819
Orient
-
Integrated sequence
TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
Start
End
8527406/8487776 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-339/Upstream/1420731; hsa-mir-10399/Downstream/9639444;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/44644, chr7-CpG: 47/Downstream/1238256
Upstream sequence
AGAATGGGACCAGTGAGGAGTCCAGGTTGGGGGCAGGGCAGAAAAAAGCTCTTGACAGCTGGGGATTTGGAGTTGCAGTTTGTTCTTTCATTAGCATTTT
Downstream sequence
GACCGTGGGACATGAGACAGCTTCGGACTGTGGGAAGGGCTCACAGTTTAATATTAGAGGAGGTGTTTTGAATTTCTCTTTCAACACCAGATTGCCTTAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.