Fusion event
HBV-chr1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
ACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGG| |GGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTC
End
185664789/185695657 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/5257267; hsa-mir-1182/Downstream/7020671;
Upstream sequence
TATAGATTCTTTCAAAAAGAAAGGTAGAATGGATGAACATTGTCTGAAAATAACTTGAGACTTATGATTGGATATTTAGAAATTTATAATTCAGATTCAG
Downstream sequence
TGCACTTCAGAATGTTTTCTCTCTGAGACCCTTGTTTACCACTTTTTGTTCAACTACCTTGAAAAATTAGTTTTGGGTTTCTTAAGGATTGAAGAGACTT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.