VISDB Viral Integration Site DataBase

VIS ID

TVIS10011997

Fusion event

HBV-MYO3B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1828

Orient

+

Integrated sequence

AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT

Chromosome

chr2

Cytoband

q31.1

Reference genome

Start

End

171274932/170418422 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1-3p

Nearest miRNA

hsa-mir-128-1/Upstream/1835404; hsa-mir-10b/Downstream/4749211;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/590303, chr2-CpG: 44/Downstream/293390

Upstream sequence

CTTCTACATAACTAAGCTGAGTTAAAATGCATCTTTTTATTAGCAGAGGCATTATTGTATTAATATCATCGCTACTAAATTTTCTCTTTGCAAAACTAGA

Downstream sequence

ATTTTAAGCTGGAATCTGGAGAAGTGTGATTTCCCTGGAAAAGAGTTTGTAGACCTCTTTGTTTGTGAAAAGTGCATCCCTAGGTCTTCATAAAAGCTCT