VISDB Viral Integration Site DataBase

VIS ID

TVIS10012006

Fusion event

HBV-IPCEF1 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1432

Orient

-

Integrated sequence

CTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGT| |CCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACC

Chromosome

chr6

Cytoband

q25.2

Reference genome

Start

End

154477145/154156010 (Hg38)

Orient

+

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-let-7b-5p ; hsa-mir-521 ; hsa-mir-5006-3p ; hsa-mir-3620-5p ; hsa-mir-4755-5p ; hsa-mir-1587 ; hsa-mir-4674 ; hsa-mir-623 ; hsa-mir-664b-5p ; hsa-mir-8064 ; hsa-mir-6832-3p ; hsa-mir-216b-3p ; hsa-mir-5582-5p ; hsa-mir-665 ; hsa-mir-6771-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-676-5p ; hsa-mir-4649-3p ; hsa-mir-6746-5p ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6753-5p ; hsa-mir-34b-3p

Nearest miRNA

hsa-mir-10398/Upstream/3053234; hsa-mir-1202/Downstream/697350;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/116137, chr6-CpG: 141/Downstream/353416

Upstream sequence

ACTTCAACCTTTGAAAGGAAGATTCCATTATTTAGACAATTGGAAAAGAAGACAAAAGACTAAAAACATTGTTGTTAATCAGGATCTGCCTTAGAGTTAA

Downstream sequence

AGTTTGGTCTCTAACATTTGACAGCACATGCCTCAAAAAGCAAACAAAATAAACACTCTCCATTTCTTTAAATATATGTTTTTCATCCAAGGATCACACA