VISDB Viral Integration Site DataBase

VIS ID

TVIS10012011

Fusion event

HBV-SDC2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1546

Orient

-

Integrated sequence

ATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGA| |CTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCA

Chromosome

chr8

Cytoband

q22.1

Reference genome

Start

End

97587829/96575601 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-3202 ; hsa-mir-2467-3p ; hsa-mir-3616-3p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-3179 ; hsa-mir-6847-5p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-577 ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p

Nearest miRNA

hsa-mir-12123/Upstream/1502605; hsa-mir-10400/Downstream/1818044;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/80222, chr8-CpG: 67/Downstream/69345

Upstream sequence

cgcccaggctggagtgcagtggtgcaatctcagctcactgtaacctccacttcctgggttcaaatgattctcctgcctcaccttccttagtagccaggat

Downstream sequence

GGGGTTGGTGAGGATGGCAGTAGGAGCCAAGTTCTGAGTTCTGTTCTGTTGACATAACTGTTGAATCACTTCCCCCCACTCACTTGTTCAAGGAGGCAAG