Fusion event
HBV-chr16 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|Polymerase|
Integrated sequence
ACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGA| |TCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCAT
End
62075876/62041972 (Hg38)
Nearest miRNA
hsa-mir-1225/Upstream/4269620; hsa-mir-11401/Downstream/5160349;
Upstream sequence
AATTTTCCAGAAGTTTCATACACTCTAGTAATCAGGCAAATAAAAGAAGGTAAGTTGCTCCCTAGGAAGAAATTCTGTTTTGTtcctcactccaccacgg
Downstream sequence
accagctataaggcttttgatgcaaagtgattaaactttcaatggattttaagtttgtgtctccataagagtgcataatacttctttccatcctcagggg
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.