Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012039
Fusion event
HBV-EHBP1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1890
Orient
+
Integrated sequence
ATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGG| |TGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATC
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
Start
End
63059776/62832641 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1301/Upstream/626724; hsa-mir-10b/Downstream/1508106;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/126423, chr2-CpG: 24/Downstream/212351
Upstream sequence
tgctcacttcgtttctctgtgtctctgtgtcattttggtaacttttgcaatatttcacactttttcattattattatatctgttatagtgatctatgacc
Downstream sequence
aatgatctttgatgttactattgtaattattttgaggtgccatgaattgcacccatttaagacagcaaacttaatcaagtgtgttctgactgatccacca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.