VISDB Viral Integration Site DataBase

VIS ID

TVIS10012051

Fusion event

HBV-JAZF1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1815

Orient

-

Integrated sequence

ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC

Chromosome

chr7

Cytoband

p15.1

Reference genome

Start

End

28154651/28115032 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-31-5p ; hsa-mir-96-5p ; hsa-let-7e-5p ; hsa-let-7a-5p ; hsa-mir-8063 ; hsa-let-7c-3p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-379-3p ; hsa-mir-4666a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-216b-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-377-3p ; hsa-mir-5583-5p ; hsa-mir-3129-3p ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-200c-3p

Nearest miRNA

hsa-mir-1183/Upstream/945469; hsa-mir-10399/Downstream/1565702;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/374050, chr7-CpG: 144/Downstream/64379

Upstream sequence

AAACAAACTTGAACAAAACCATTTGGCAATTTTCATATAATCAAAAGAGCTTATTCATATCAATAAGAAAATTCTAAGATGCCAAAAAGAAAGTTGGTAC

Downstream sequence

AAAGGGTCTCTGTAGGCATGTAGGAGGCAAGAGGTTTTAAAGCAGTGAAATGACACATGTAGGTTCTGTTGTTGTTTTTAAGTAATTCTGGCAGACATGC