VISDB Viral Integration Site DataBase

VIS ID

TVIS10012063

Fusion event

HBV-SLC1A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1821

Orient

-

Integrated sequence

TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA

Chromosome

chr9

Cytoband

p24.2

Reference genome

Start

End

4543876/4543876 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-96-5p ; hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-186-5p ; hsa-mir-500a-5p ; hsa-mir-629-3p ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-4685-3p ; hsa-mir-4713-5p ; hsa-mir-6867-3p ; hsa-mir-6868-3p ; hsa-mir-7113-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-758-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6744-5p ; hsa-mir-6849-3p ; hsa-mir-5586-5p ; hsa-mir-6835-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4641 ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-6832-3p ; hsa-mir-652-5p

Nearest miRNA

hsa-mir-1302-9/Upstream/4513595; hsa-let-7a-1/Downstream/306421;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/52458, chr9-CpG: 66/Downstream/118376

Upstream sequence

ttttggaataggtgtggtgtggtgttgaaaaaaatgtgtattctgttgatttggggtggagagttctgtagatgtctattatgtctgcttggtgcagagc

Downstream sequence

AACTATAAAATATGTAAAATAgccaagcatggtggttcacacctgtaatcccagcactttcggaagtcgaggtgggcagatcacttgaggccaggagttc