VISDB Viral Integration Site DataBase

VIS ID

TVIS10012064

Fusion event

HBV-SLC1A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1861

Orient

+

Integrated sequence

AAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTA| |CTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCC

Chromosome

chr9

Cytoband

p24.2

Reference genome

Start

End

4543885/4543885 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-96-5p ; hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-186-5p ; hsa-mir-500a-5p ; hsa-mir-629-3p ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-4685-3p ; hsa-mir-4713-5p ; hsa-mir-6867-3p ; hsa-mir-6868-3p ; hsa-mir-7113-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-758-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6744-5p ; hsa-mir-6849-3p ; hsa-mir-5586-5p ; hsa-mir-6835-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4641 ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-6832-3p ; hsa-mir-652-5p

Nearest miRNA

hsa-mir-1302-9/Upstream/4513604; hsa-let-7a-1/Downstream/306412;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/52467, chr9-CpG: 66/Downstream/118367

Upstream sequence

ttccacttcttcaaagaagccctatctaatgtccTTCTCCAGAAATATTTGCTTTATCTTCTGAAACCTTCTCTGCccttccctctttccttccttcctt

Downstream sequence

ATATGTAAAATAgccaagcatggtggttcacacctgtaatcccagcactttcggaagtcgaggtgggcagatcacttgaggccaggagttcgagaccagc