Basic Information
VIS ID
TVIS10012073
Fusion event
HBV-LOC101929279 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1826
Orient
-
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAA
Host Sequence
Chromosome
chr10
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
30503326/30214397 (Hg38)
End
30503326/30214397 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC101929279
Nearest miRNA
hsa-mir-1265/Upstream/612051; hsa-mir-107/Downstream/154200;
Nearest TSS
ENST00000439456/Upstream/98903; ENST00000375322/Downstream/134580;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/154678, chr10-CpG: 26/Downstream/134635
Nearby gene
JCAD(-154838) ; MTPAP(+95404) ;
Upstream sequence
tcccagcactgtgggaagccaaggcaggcagatcatctgaggtcaggagtttgagtccagcctggccaatagagtgagacctcatctctactaaaataca
Downstream sequence
agattagccaggcgtggtgatgggcacctgtaatcccagctactcaggaggctaaggcaggagaatcacttgaactcgggaggtggaggttgcagtgagc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate