VISDB Viral Integration Site DataBase

VIS ID

TVIS10012079

Fusion event

HBV-MTA2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2323

Orient

-

Integrated sequence

CTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTAT| |CAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAG

Chromosome

chr11

Cytoband

q12.3

Reference genome

Start

End

62368854/62601382 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-559 ; hsa-mir-661 ; hsa-mir-146a-5p ; hsa-mir-335-5p ; hsa-mir-34a-5p ; hsa-mir-125b-2-3p ; hsa-mir-615-3p ; hsa-mir-548a-3p ; hsa-mir-505-3p ; hsa-mir-423-3p ; hsa-mir-365a-3p ; hsa-mir-186-5p ; hsa-mir-222-3p

Nearest miRNA

hsa-mir-129-2/Upstream/34311; hsa-let-7a-2/Downstream/188433;

Nearest TSS

Nearest CpG islands

chr11-CpG: 207/Target, None/Upstream, None/Downstream

Upstream sequence

CTCCCGGTTCCGGTTCCGGTCCGCGCTCCGGTCCACGCTGCCCCATACGCTGCGCCTCGCGCCACCCGGTGCCGAGCCCCTCAGGTCCCTACCCCAACCT

Downstream sequence

CTCCCGCCCCGGGCCCCGTATCCCTGCGCCCGGTACTCACCTCCCACCCGGTACATGTTGGCCGCCATGGCCGTTCCCGCCGCCGCCTCCGGCCGCACAA