Fusion event
HBV-chr18 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|Polymerase|
Integrated sequence
CACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAG| |GTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTC
End
18519012/20939051 (Hg38)
Nearest miRNA
hsa-mir-3156-2/Upstream/6108809; hsa-mir-1-2/Downstream/744467;
Nearest cancer related gene
Upstream sequence
tcgaaatgtccacttccacatactacaaaaagagtgtttcaaaccttctctatgaaagggaatgttcaactctatgagttgaatgcaaacatcagaacga
Downstream sequence
aatttctgagaatgctgctgtccactttttatatgaatgcgcgctttcaacgaaatcctcaaagcaatccaaatatccacttgcagattccacaaaaaga
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.