VISDB Viral Integration Site DataBase

VIS ID

TVIS10012113

Fusion event

HBV-CDH12 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

331

Orient

+

Integrated sequence

CTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCA| |ATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCAT

Chromosome

chr5

Cytoband

p14.3

Reference genome

Start

End

22193069/22192960 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-4455 ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-759 ; hsa-mir-4433a-5p ; hsa-mir-4433b-5p ; hsa-mir-4646-3p

Nearest miRNA

hsa-mir-10397/Upstream/5036968; hsa-mir-103a-1/Downstream/9743142;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/733217, chr5-CpG: 68/Downstream/2997434

Upstream sequence

ccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccct

Downstream sequence

GACATGGCTATATAGTTAAGGAAGTCGGAAAAAAACTGAGATTTGTGATACTGGAATGGAGTGTGGAAAAAAAAATCATAGTTTAGTAAGACACTCAGGT