Basic Information
VIS ID
TVIS10012124
Fusion event
HBV-CD99P1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2131
Orient
-
Integrated sequence
TCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGG| |AAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTT
Host Sequence
Chromosome
chrY
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
2484820/2616779 (Hg38)
End
2484820/2616779 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
CD99P1
Nearest miRNA
hsa-mir-3690-2/Upstream/7525; hsa-mir-12120/Downstream/1989341;
Nearest TSS
ENST00000430575/Downstream/170920;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/7123, chrY-CpG: 107/Downstream/74150
Upstream sequence
ccattctattccagtccattagtttcgactccattgcattcgagtgcattccattccgtggctgtccattccattccgtttgatgccattccatacgatt
Downstream sequence
tcagtgggccatggagacttcttcttctgtgtatgggatactgtgtcttttattcttctattctggtatgtcctccctgatttctagtcatttttgaatt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate