Basic Information
VIS ID
TVIS10012170
Fusion event
HBV-chrY integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2818
Orient
+
Integrated sequence
AGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGG| |TCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTC
Host Sequence
Chromosome
chrY
Cytoband
q12
Reference genome
End
58909384/56681485 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/43202219;
Nearby gene
SPRY3(+191073) ;
Upstream sequence
cagtacatttcattccaatcccatccaatcccatctactccattcaattcctttccattccatttgatttgattccattgatttgattccattcagtttg
Downstream sequence
ctttccattccatttgatttgattccattgatttgattccattcagtttgattccattccgtgaaatttcgttccattctattccattgcattactttcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate