Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012176
Fusion event
HBV-CD5L integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2164
Orient
+
Integrated sequence
CTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTT| |ATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTC
Host Sequence
Chromosome
chr1
Cytoband
q23.1
Reference genome
End
157804651/157834861 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/898617; hsa-mir-1182/Downstream/2065118;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/639516, chr1-CpG: 28/Downstream/144069
Upstream sequence
AAGAGAGCGTGTCTGTTCTCTGCCAGAACATGGTCTTCTCAGTAAAGGCGGCCCAATGGACACATCTCACAGTTCTTGGTGTTCAGTACAAGGCATGCTA
Downstream sequence
AAGTGCTTAACACTGCCTCATAGATGCCTGCTGAAAGAATGAATGAGGGAATCAATGAAGAAAATGTAACTTCCAAATTCAAAGCTGAATCATTATcatt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.