Basic Information
VIS ID
TVIS10012181
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1806
Orient
-
Integrated sequence
ACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGC| |ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
161435728/161465938 (Hg38)
End
161435728/161465938 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/238677; hsa-mir-1182/Downstream/691169;
Nearest TSS
ENST00000473358/Upstream/24942; ENST00000473080/Downstream/4585;
Nearest CpG islands
chr1-CpG: 2148/Target, None/Upstream, None/Downstream
Nearby gene
CFAP126(-98064) ; FCGR2A(+39477) ;
Upstream sequence
TTTCACTTCACGGAACACCGCCAGGCACCACGGGCTTGCAGCCACTCGCACCACCCCTTCTCTTCACATTTCACCGCCTCGACctctctctctctctctc
Downstream sequence
tctctctctctctctctctgtctctctctgtctctctcCCCCCCCCCCCCTCGCTGGCTCCCCACATCCAGAAAATGATGCCATGGTTGCCCTTCCAGTA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate