VISDB Viral Integration Site DataBase

VIS ID

TVIS10012189

Fusion event

HBV-PRKG1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1782

Orient

-

Integrated sequence

TGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGG| |CTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGT

Chromosome

chr10

Cytoband

q21.1

Reference genome

Start

End

53058122/51298362 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-218-5p ; hsa-mir-3591-5p ; hsa-mir-1273e ; hsa-mir-921 ; hsa-mir-3606-5p

Nearest miRNA

hsa-mir-1265/Upstream/2312775; hsa-mir-107/Downstream/1211;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/223370, chr10-CpG: 40/Downstream/401129

Upstream sequence

GCCACTACTTCAAAAAATGTGGTTTATTTTATAGGCAAAGAAAAGGCACTGAATTGAATATTATGACTAAGCTTGTGATCTTAAAAGATTTAGGTTCTGA

Downstream sequence

GTTGgacctgattaaaaattccagctccaccaattactgattacatgaacctggtgggagttgttcagtctttccatactccaggttcttcctttttcaa