VISDB Viral Integration Site DataBase

VIS ID

TVIS10012191

Fusion event

HBV-ZCCHC24 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1204

Orient

-

Integrated sequence

CAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCAC| |TGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGC

Chromosome

chr10

Cytoband

q22.3

Reference genome

Start

End

81187034/79427278 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-335-5p ; hsa-mir-1301-3p ; hsa-mir-744-5p ; hsa-mir-346 ; hsa-mir-4446-5p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-629-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-7106-5p ; hsa-mir-149-3p ; hsa-mir-3192-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-1224-3p ; hsa-mir-6765-3p ; hsa-mir-7851-3p ; hsa-mir-4290 ; hsa-mir-1233-3p ; hsa-mir-4687-5p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-6832-3p ; hsa-mir-3938 ; hsa-mir-3936 ; hsa-mir-211-5p ; hsa-mir-204-5p

Nearest miRNA

hsa-mir-1265/Upstream/3874725; hsa-mir-107/Downstream/6837416;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/40837, chr10-CpG: 112/Downstream/17418

Upstream sequence

cactcaaatgaatgaagcaaaaactgacagaattgaagaaagaaatagacaaacaataatttctggaggcttaaatatccccacttaaaataataataaa

Downstream sequence

agaactgggcagaatatcaacaaagcaggaggagacatagacatcactatgaaccaactagacctaacagacatctataaaacactccaccaaacaacag