VISDB Viral Integration Site DataBase

VIS ID

TVIS10012203

Fusion event

HBV-FAM168A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2558

Orient

+

Integrated sequence

CCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATT| |TACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCC

Chromosome

chr11

Cytoband

q13.4

Reference genome

Start

End

73176383/73465338 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-10a-5p ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-555 ; hsa-mir-765 ; hsa-mir-5702 ; hsa-mir-6861-5p ; hsa-mir-6742-3p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-331-3p ; hsa-mir-3139 ; hsa-mir-708-5p ; hsa-mir-28-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-6801-5p ; hsa-mir-4266 ; hsa-mir-766-5p ; hsa-mir-3202 ; hsa-mir-3179 ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-450a-2-3p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-4722-5p ; hsa-mir-6731-5p ; hsa-mir-1827 ; hsa-mir-4768-3p ; hsa-mir-4259 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6888-5p ; hsa-mir-548e-5p

Nearest miRNA

hsa-mir-10392/Upstream/681746; hsa-let-7a-2/Downstream/933899;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/88101, chr11-CpG: 63/Downstream/132416

Upstream sequence

aacacatactAGATAGACCCCTGGGTGATGCTTGGACACTGACACAATCAGAACATTTTAGAAAAGAAAAGATGAGAAGAATGTTGAGGTCTTGACTACA

Downstream sequence

CTCCAAAATTCTAACAGAAAAACCTTTATGAAGCTTTTGGAAAAAGAAATGCCCTGGTCTATAAACAGCCCACTGTCATGGTGAATCTAGGTAAAGGGTA