VISDB Viral Integration Site DataBase

VIS ID

TVIS10012217

Fusion event

HBV-GPD1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1731

Orient

-

Integrated sequence

ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA| |CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACC

Chromosome

chr12

Cytoband

q13.12

Reference genome

Start

End

50498857/50105074 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-3157-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-18b-3p ; hsa-mir-18a-3p ; hsa-mir-5088-3p ; hsa-mir-6752-3p ; hsa-mir-3162-3p ; hsa-mir-361-3p ; hsa-mir-6793-3p

Nearest miRNA

hsa-mir-1244-3/Upstream/1333037; hsa-let-7i/Downstream/129068;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/19528, chr12-CpG: 67/Downstream/6523

Upstream sequence

ACAAGTTGGTCTCCATGGCAGCCAAAGACTGGGCTCCCAGACTTGGGGTCCAGTAGTGCCTGCCTCCGGCACTAATCCTGTTACTCATTCACTGAGTGAG

Downstream sequence

TAGCCGACTTGGAGGCTGCTCCTTGGACTTACGGTCTTTGGTCAAATCCACGTGGCTCTCCCCACCTGGAAAGGGGAAGCAGGGAAGAGAGCAGAAAGGC