VISDB Viral Integration Site DataBase

VIS ID

TVIS10012221

Fusion event

HBV-NEMP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1632

Orient

-

Integrated sequence

TCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCA| |CCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGAC

Chromosome

chr12

Cytoband

q13.3

Reference genome

Start

End

57473256/57079473 (Hg38)

Orient

-

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-196a-5p ; hsa-mir-192-5p ; hsa-mir-24-3p ; hsa-let-7d-5p ; hsa-mir-93-3p ; hsa-mir-155-5p ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p

Nearest miRNA

hsa-mir-1244-3/Upstream/2742159; hsa-let-7i/Downstream/115031;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/637, chr12-CpG: 162/Downstream/7541

Upstream sequence

TAAAATTAATGTTAGGATTAAGAAAGATtcatttattcctcttatcatcttgtgagacaaatataattctctccatttaagaagccaaagccaagacagc

Downstream sequence

cacaggaacctgcccaagatttcatagttcatctggtctgtgatcccaacctaaatcctactgactccaaagccggagttatttatatggattagctgct