VISDB Viral Integration Site DataBase

VIS ID

TVIS10012226

Fusion event

HBV-C12orf29 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2962

Orient

-

Integrated sequence

TTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAA| |GGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAG

Chromosome

chr12

Cytoband

q21.32

Reference genome

Start

End

88431764/88037987 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-1226-3p ; hsa-mir-181a-5p ; hsa-mir-15b-3p ; hsa-mir-4719 ; hsa-mir-8063

Nearest miRNA

hsa-let-7i/Upstream/1292838; hsa-mir-1178/Downstream/6523802;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/2158, chr12-CpG: 34/Downstream/103971

Upstream sequence

AGGAACCCAAGAAACTGCCTTTTCCTCATCCTTGGTGCCCTTCTTCTTCCTGACAGTAGAAAAACCATAAATTAAATATGTAAACAGCTGACTACTGATA

Downstream sequence

AAGCTGAAAGGGACAAAAAGTGAGTACTCTCAAAGCAAACAAACTCAAAGGAAAAACAAAAGGCAAGTGATTCTTACTAGTTTTAACGGTGAAAATTGTT