VISDB Viral Integration Site DataBase

VIS ID

TVIS10012228

Fusion event

HBV-MRPL42 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1671

Orient

-

Integrated sequence

CCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGG| |ACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTT

Chromosome

chr12

Cytoband

q22

Reference genome

Start

End

93881271/93487495 (Hg38)

Orient

+

Location type

splicing

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-101-3p ; hsa-mir-186-5p

Nearest miRNA

hsa-let-7i/Upstream/6742346; hsa-mir-1178/Downstream/1074294;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/19732, chr12-CpG: 297/Downstream/82692

Upstream sequence

TAGTGAATTACTGAATATGGTAATTGTTTTATTGTGATCTCAAACAAATGCTGGCTAACATTCCCACATCTTCATGATGTTTGTTACTGATTATTTTGTA

Downstream sequence

GCCTATCCCTCGGCCAGATCCTGTGCATAATAATGAAGAAACACATGATCAAGTGCTGAAAACCAGATTGGAAGAAAAAGTTGAACACCTTGAGGAAGGA