Basic Information
VIS ID
TVIS10012236
Fusion event
HBV-MIR548AI integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2187
Orient
-
Integrated sequence
GGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTA| |AAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTC
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
End
29911169/29441963 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-208a/Upstream/1808685; hsa-mir-1185-1/Downstream/1572683;
Upstream sequence
CCTGGGAAAACAGTaataatgataattcctaactaattttaacaacttcattattaataacatatgcattatgaccaattcttacaaaaactttacatga
Downstream sequence
tatgctatttttcctatttcatagatgaggaattaggttgattcaggttaaatattttccaagactgcacaggtggtaaatagcaaaatcgggaatattt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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