Basic Information
VIS ID
TVIS10012245
Fusion event
HBV-CCDC32 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1705
Orient
-
Integrated sequence
TCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCA| |TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
End
40833096/40540897 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1233-1/Upstream/3567996; hsa-mir-10393/Downstream/1150688;
Nearby gene
MRPL42P5(-8347) ; CCDC32(+12202) ;
Upstream sequence
ATGTTCCAAGCTCACATATGAGTGTTGAACAGGTGCCAGCCTGGAGCGTCCATTGCCCTGGTGCCCTCAGTCCAGAGAGCCCAGTGAGAAGCTGGGCCAA
Downstream sequence
GAAGGAAGACTTGAACCCAAGAGAGCAGTGTGTGGACATTCAGACTAGGCTGGGCTGAACTCACCCCCGGGGAGAACCACTTCCCACACTGGGCCACAGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate