VISDB Viral Integration Site DataBase

VIS ID

TVIS10012261

Fusion event

HBV-CBX4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

470

Orient

-

Integrated sequence

ATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCC| |CGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGC

Chromosome

chr17

Cytoband

q25.3

Reference genome

Start

End

77811860/79838061 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-101-3p ; hsa-mir-328-3p ; hsa-mir-325 ; hsa-mir-552-5p ; hsa-mir-628-3p ; hsa-mir-374a-5p ; hsa-mir-498 ; hsa-mir-7702 ; hsa-mir-6079 ; hsa-mir-633 ; hsa-mir-671-5p ; hsa-mir-4699-3p ; hsa-mir-6828-5p ; hsa-mir-4259 ; hsa-mir-4715-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-590-5p ; hsa-mir-21-5p ; hsa-mir-508-3p ; hsa-mir-302c-5p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-520g-5p ; hsa-mir-3614-3p ; hsa-mir-646 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-5589-3p ; hsa-mir-129-5p ; hsa-mir-376c-3p ; hsa-mir-136-5p ; hsa-mir-889-3p

Nearest miRNA

hsa-mir-10226/Upstream/130812; hsa-mir-1250/Downstream/260767;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/2814, chr17-CpG: 488/Downstream/1125

Upstream sequence

CGCGGCCTCCAGGTGGGGAGTGACATAAGGCCCTACTCTGTCTTTATGAACATTTAGCCGTGGATGTGGAAGGTAGATTTCCGCAGGCCTGACGTAGTCC

Downstream sequence

CTGATACACAGCCCCCCCCTCAAATAAACACGCAAGGGCAGGAAGAAAGGGGAGGGGTAAGGAAAATGAAACTAGCAGTTTATTTTGCAGTTGTCAAGAA