Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10012272
Fusion event
HBV-SLC4A10 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1731
Orient
-
Integrated sequence
ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA| |CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACC
Host Sequence
Chromosome
chr2
Cytoband
q24.2
Reference genome
End
162584497/161727987 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-128-1/Upstream/1320105; hsa-mir-10b/Downstream/6854956;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/220098, chr2-CpG: 63/Downstream/345736
Upstream sequence
aaatgcacagcataataaataaaaatagtaccacaccaagggcacatcatcatcaaattgcaaaagactgagattaaagagattctaaaagctctgagaa
Downstream sequence
aaagaactgacaaacttctatcaagcctcataaataaaaatgaaagtgaagacacaaattaccaatatcaggaatgagagagtgaatattactatagact
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.