VISDB Viral Integration Site DataBase

VIS ID

TVIS10012282

Fusion event

HBV-REL integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1789

Orient

-

Integrated sequence

GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG

Chromosome

chr2

Cytoband

p16.1

Reference genome

Start

End

61153097/60925962 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-3611 ; hsa-mir-1257 ; hsa-mir-95-5p ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-511-5p ; hsa-mir-1229-5p ; hsa-mir-1225-5p ; hsa-mir-4540 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-4711-3p ; hsa-mir-6830-3p ; hsa-mir-503-3p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-3121-5p ; hsa-mir-6838-3p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-4326 ; hsa-mir-4433a-5p ; hsa-mir-1224-3p ; hsa-mir-5588-3p ; hsa-mir-4709-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-145-5p ; hsa-mir-4446-5p ; hsa-mir-7977 ; hsa-mir-767-5p ; hsa-mir-4729 ; hsa-mir-3065-3p ; hsa-mir-501-5p ; hsa-mir-135a-3p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-5584-5p ; hsa-mir-500a-5p ; hsa-mir-3121-3p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-3689d ; hsa-mir-7641 ; hsa-mir-6879-3p ; hsa-mir-3650 ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-4746-3p ; hsa-mir-4695-3p ; hsa-mir-6787-3p ; hsa-mir-500b-3p ; hsa-mir-2054 ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-3686 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-4742-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-4778-5p ; hsa-mir-380-3p ; hsa-mir-34c-3p ; hsa-mir-3163 ; hsa-mir-300 ; hsa-mir-381-3p ; hsa-mir-1264 ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-6516-5p ; hsa-mir-3678-3p ; hsa-mir-2467-3p ; hsa-mir-1273h-3p ; hsa-mir-4524a-3p ; hsa-mir-656-3p ; hsa-mir-329-5p ; hsa-mir-4524b-3p ; hsa-mir-3927-5p ; hsa-mir-4286 ; hsa-mir-136-3p ; hsa-mir-548c-3p ; hsa-mir-6509-5p ; hsa-mir-4713-5p ; hsa-mir-331-5p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6887-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-4678 ; hsa-mir-3064-3p ; hsa-mir-1227-3p ; hsa-mir-1250-3p ; hsa-mir-4289 ; hsa-mir-455-5p ; hsa-mir-382-3p ; hsa-mir-302b-5p ; hsa-mir-874-3p ; hsa-mir-6873-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-4261 ; hsa-mir-146b-3p ; hsa-mir-6799-3p ; hsa-mir-3173-5p ; hsa-mir-7976 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4716-5p ; hsa-mir-3688-3p ; hsa-mir-371b-3p ; hsa-mir-4802-3p ; hsa-mir-7-5p ; hsa-mir-1304-3p ; hsa-mir-215-3p ; hsa-mir-3664-5p ; hsa-mir-4639-3p ; hsa-mir-6773-3p ; hsa-mir-6794-3p

Nearest miRNA

hsa-mir-1301/Upstream/538517; hsa-mir-10b/Downstream/1279864;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/44081, chr2-CpG: 89/Downstream/139771

Nearby gene

REL(-2919) ; PUS10(+14451) ;

Nearest cancer related gene

REL(OG, No orient, 0)

Upstream sequence

GTGTTTAGAATATTTTTTTAAAACTAAATAAGTGTTGGCTAGTTTTGCGGTGTAAGCAGAATTAAGGTTCTGCTACCTCTGTGTGTAGAATATTCCCAAT

Downstream sequence

GGATTTTTCATTTTTCAGGTGCTATTTTTTGACCCTGTATAGACTTTAATTTAAAATGAATTTGGTAACGTTTCTCCTCTGTCTCTACATATATTCATGC